The View: Eye Innovation at the Save Sight Institute
Autumn 2019 - See the Future
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Lee M-H H, Ooi K G-J, Burlutsky G, Gopinath B, Mitchell P, Watson S. The Association of dyslipidemia and oral statin use, and dry eye symptoms in the Blue Mountains Eye Study. Clin Exp Ophthalmol.
Bobba S, Di Girolamo N, Munsie M, Chen F, Pebay A, Harkin D, Hewitt A, O’Connor M, McLenachan A, Shadforth AMA, Watson SL. The current state of stem cell therapy for ocular disease. Exp Eye Res. 2018, 177 :65-75
Zada M, Cabrera-Aguas M, Branley M, Azar D, Watson S. Microbial keratitis associated with long-term orthokeratology. Clin Exp Ophthalmol 2018.
Watson S, Maria Cabrera-Aguas M, Khoo P, Pratama R, Gatus BJ, Gulholm T, El-Nasser J, Lahra MM. The Keratitis Antimicrobial Resistance Surveillance Program, Sydney, Australia. 2016 Annual Report. Clin Exp Ophthalmol. 2018 Jul 25. doi: 10.1111/ceo.13364.
Watson SL, Leung V. Interventions for recurrent corneal erosion. Cochrane Eyes and Vision Group. 2018. Issue 7. Art. No.: CD001861
Watson S, Cabrera-Aguas M, Khoo P. Common Eye Infections. Aust Prescr, 2018;41:67–721
Bobba S, Devlin C, Di Girolamo N, Wakefield D, McCluskey P, Chan E, Daniell M, Watson S. Incidence, Clinical Features and Diagnosis of Cicatrising Conjunctivitis in Australia and New Zealand. Eye 2018.
Maria Cabrera-Aguas M, Robaei D, McCluskey P, Watson SL. Clinical translation of recommendations from randomised trials for management of herpes simplex virus keratitis. Clin Exp Ophthalmol 2018. May 10. doi: 10.1111/ceo.13319.
Robaei D, Chan U-T, Khoo P, Cherepanoff S, Li Y-C, Hanrahan J, Watson S. Corneal biopsy for diagnosis of recalcitrant microbial keratitis. Graefes Arch Clin Exp Ophthalmol. 2018. Aug;256(8):1527-1533.
Richardson A, Park M, Watson SL, Wakefield D, Di Girolamo N. Visualizing the fate of transplanted K14-Confetti corneal epithelial cells in a mouse model of limbal stem cell deficiency. Invest Ophthalmol Vis Sci. 2018, 59: 1630-1640. doi:10.1167/iovs.17-23557
Leahy KE, Madigan MC, Sarris M, Watson SL, McCluskey P, White AJ. Investigation of corneal endothelial changes post selective laser trabeculoplasty. Clin Exp Ophthalmol. 2018 Feb 14. doi: 10.1111/ceo.13172.
Nguyen KN, Bobba S, Richardson A, Park M, Watson SL, Wakefield D, Di Girolamo N. Native and synthetic scaffolds for limbal epithelial stem cell transplantation. Acta Biomater. 2018 Jan;65:21-35. doi: 10.1016/j.actbio.2017.10.037. Epub 2017 Nov 6.
Oh L, Wong E, Beshay N, Di Girolamo N, Watson S. Applications and efficacy of topical N-acetyl-cysteine in a Tertiary Eye Referral Centre. RANZCO October 2017.
Bosch M, Knecht PB& Watson S. Ocular Problems in Extreme Sports. (2017). 41-52. 10.1007/978-3-319-28265-7_5.
Rao A, Watson S. Possible role of aqueous humour dynamics in Descemet's membrane detachment resolution. Clin Exp Ophthalmol. 2017 Nov;45(8):834-836. doi: 10.1111/ceo.12957. Epub 2017 May 11.
Beshay N, Keay L, Dunn H, Kamalden TA, Hoskin AK, Watson SL. The epidemiology of Open Globe Injuries presenting to a tertiary referral eye hospital in Australia. Injury. 2017 Jul;48(7):1348-1354. doi: 10.1016/j.injury.2017.04.035. Epub 2017 Apr 18.
Oh L, Watson S. Light-based epilation device-related injury to the cornea. Med J Aust. 2017 Mar 6;206(4):157.
Watson S. Meibomian gland disease and the microbiotome: is it time for ocular probiotics? Clin Exp Ophthalmol. 2017 Mar;45(2):103-104. doi: 10.1111/ceo.12901.
Samarawickrama C, Li YC, Carnt N, Willcox M, Dutta D and Watson S. Reducing oral contamination during corneal scrapes. BMJ Open Ophthalmol. 2017; 1(1): e000044. doi: 10.1136/bmjophth-2016-000044
Höllhumer R, Watson S, Beckingsale P. Persistent Epithelial Defects and Corneal Opacity After Collagen Cross-Linking With Substitution of Dextran (T-500) With Dextran Sulfate in Compounded Topical Riboflavin. Cornea. 2017 Mar;36(3):382-385. doi: 10.1097/ICO.0000000000001134.
Bobba S, Di Girolamo N, & Watson S. (2016). Contact lens delivery of stem cells for restoring the ocular surface. 219-239. 10.1016/B978-0-08-100147-9.00009-2.
Mathewson PA, Williams GP, Watson SL, Hodson J, Bron AJ, Rauz S. Defining Ocular Surface Disease Activity and Damage Indices by an International Delphi Consultation. Ocul Surf. 2017 Jan;15(1):97-111. doi: 10.1016/j.jtos.2016.08.005.
Bobba S, Di Girolamo N, Mills R, Daniell M, Chan E, Harkin DG, Cronin BG, Crawford G, McGhee C, Watson S. Nature and incidence of severe limbal stem cell deficiency in Australia and New Zealand. Clin Exp Ophthalmol. 2017 Mar;45(2):174-181. doi: 10.1111/ceo.12813.
Chiu M, Dillon A, Watson S. J Paediatr Child Health. Vitamin A deficiency and xerophthalmia in children of a developed country. 2016 Jul;52(7):699-703. doi: 10.1111/jpc.13243.
Höllhumer R, Zairani Mz A, Watson S. Hemorrhagic Descemet Membrane Detachment Following Syphilitic Interstitial Keratitis. Cornea. 2016 Sep;35(9):1255-6. doi: 10.1097/ICO.0000000000000889.
Carnt N, Robaei D, Watson SL, Minassian DC, Dart JK. The Impact of Topical Corticosteroids Used in Conjunction with Antiamoebic Therapy on the Outcome of Acanthamoeba Keratitis. Ophthalmology. 2016 May;123(5):984-90. doi: 10.1016/j.ophtha.2016.01.020.
Robaei D, Carnt N, Watson S. Established and emerging ancillary techniques in management of microbial keratitis: a review. Br J Ophthalmol. 2016 Sep;100(9):1163-70. doi: 10.1136/bjophthalmol-2015-307371.
Bobba S, Chow S, Watson S, Di Girolamo N. Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series. Stem Cell Res Ther. 2015 Mar 12;6:23. doi: 10.1186/s13287-015-0009-1.
Chiu M, Watson S. Xerophthalmia and vitamin A deficiency in an autistic child with a restricted diet. BMJ Case Rep. 2015 Oct 5;2015. pii: bcr2015209413. doi: 10.1136/bcr-2015-209413.
Chew SK, Watson S. Use of topical retinoic acid for limbal stem cell failure: a retrospective clinical case series. Clin Exp Ophthalmol. 2016 Apr;44(3):217-8. doi: 10.1111/ceo.12663.
Cabrera-Aguas M, Robaei D, & Watson S. Clinical Translation Of Recommendations From Randomized Trials For Management Of Herpes Simplex Keratitis. Clinical and Experimental Ophthalmology. 2015 43. 49-49. 10.1111/ceo.13319.
Barkley M, Brown T, Robaei D, Watson S. (2015). Effective Diagnosis Of Acanthamoeba Keratitis Without The Need For E-Coli Seeded Plates. Clinical and Experimental Ophthalmology. 43. 84-85.
Watson S, Go C, Gunasekara G, Herrera-Bond A, Kerdraon,Y, Males J. (2015). Corneal Cross-Linking At Sydney Eye Hospital: Pilot Evaluation Of The Fight Corneal Blindness Module For Corneal Cross-Linking. Clinical and Experimental Ophthalmology. 43. 86-86.
Watson S, Go C, Gunasekara G, Herrera-Bond A, Kerdraon,Y, Males J. (2015). Corneal Cross-Linking At Sydney Eye Hospital: Pilot Evaluation Of The Fight Corneal Blindness Module For Corneal Cross-Linking. Clinical and Experimental Ophthalmology. 43. 86-86.
Inglis H, Boyle FM, Friedlander ML, Watson SL. Dry eyes and AIs: If you don't ask you won't find out. Breast. 2015 Dec;24(6):694-8. doi: 10.1016/j.breast.2015.08.008. Epub 2015 Sep 28.
Ooi KG, Wakefield D, Billson FA, Watson SL. Efficacy and Safety of Topical Atorvastatin for the Treatment of Dry Eye Associated with Blepharitis: A Pilot Study. Ophthalmic Res. 2015;54(1):26-33. doi: 10.1159/000367851.
Robaei D, Naunton M, Watson S. Seeing red: over-the-counter chloramphenicol. Clin Exp Ophthalmol. 2015 Mar;43(2):99-100. doi: 10.1111/ceo.12497.
Samarawickrama C, Cherepanoff S, Di Girolamo N, Benger R, Watson S. Unusual limbal lesion in neurofibromatosis type 1. Cornea. 2015 Mar;34(3):347-9. doi: 10.1097/ICO.0000000000000353.
Inglis H, Boyle F, Friedlander M, Watson S. Dry Eyes & AIs. Clinical and Experimental Ophthalmology. Nov 2014. 42. 65-65.
Chiu M, Watson S. Nature Of Ophthalmological Review In Children With Vitamin A Deficiency And Occurrences Of Xerophthalmia. Clinical and Experimental Ophthalmology. Nov 2014. 42. 39-39.
Chew S, Samarawickrama C, Watson S. The Role Of Topical Retinoic Acid In Ophthalmology. Clinical and Experimental Ophthalmology. Nov 2014. 42. 84-85.
Samarawickrama C, Chew S, Watson S. Retinoic acid and the ocular surface. Surv Ophthalmol. 2015 May-Jun;60(3):183-95. doi: 10.1016/j.survophthal.2014.10.001.
McDerby N, Watson SL, Robaei D, Naunton M. Inappropriate use of topical chloramphenicol results in vision loss. Clin Exp Ophthalmol. 2015 Mar;43(2):192-3. doi: 10.1111/ceo.12465.
Samarawickrama C, Leaney J, Watson S. Severe alkali burns from beer line cleaners warrant mandatory safety guidelines. Med J Aust. 2014 Jul 21;201(2):90.
Samarawickrama C, Watson S, McCluskey PJ. Rheumatoid arthritis and the eye. July 2014. Medicine Today. 15. 66-68.
Robaei D, Watson S. Corneal blindness: a global problem. Clin Exp Ophthalmol. 2014 Apr;42(3):213-4. doi: 10.1111/ceo.12330.
Mathewson P, Hodson J, Watson S, Williams G, Rauz S, OSDISS Study Group, Uveitis & Advisory Groups. An International Ocular Surface Disease Scoring System (OSDISS): Defining Activity and Damage by A Delphi Consultation. Oculoplastics. May 2014
Tan J, Wechsler AW, Watson S. Long-term adhesion of cyanoacrylate on human cornea. Clin Exp Ophthalmol. 2014 Nov;42(8):791-3. doi: 10.1111/ceo.12300. Epub 2014 Mar 11.
Tran T, Samarawickrama C, Petsoglou C, Watson S. Recent cluster of childhood microbial keratitis due to orthokeratology. Clin Exp Ophthalmol. 2014 Nov;42(8):793-4. doi: 10.1111/ceo.12302.
Watson SL, Geerling G, Dart JK. Clinical study of therapeutic ocular surface medium for persistent epithelial defect. Ophthalmic Res. 2014;51(2):82-7. doi: 10.1159/000355065.
Chiu CCM, Garside L, Watson S. Vitamin A deficiency in Australian children. Clin Experiment Ophthalmol. Nov 2013. 41.
Tan J, Watson S, Foster L. Efficacy Of Corneal Gluing Procedures. Clinical and Experimental Ophthalmology. November 2014. 41. 34-34.
Leahy K, Sarris M, Di Girolamo N, Watson S, McCluskey P, White A. Immunofluorescent Investigation Of Corneal Endothelial Changes Associated With Selective Laser Trabeculoplasty. Clinical and Experimental Ophthalmology. November 2013. 41:5-15.
Samarawickrama C, Ioannidis AS, Wechsler A, Watson S. Bilateral Corneal Infections From Steroid Prophylaxis Against Cytarabine Keratoconjunctivitis. Clinical and Experimental Ophthalmology. November 2013. 41:36-36.
Ooi KG, Wakefield D, Billson FA, Watson SL. Topical Atorvastatin For The Treatment Of Dry Eye Associated With Blepharitis. Clinical and Experimental Ophthalmology. Nov 2013. 41:35-35.
Watson S, Lee H. Interventions for recurrent corneal erosion: a Cochrane Systematic review. Eye (Lond). 2013 Nov;27(11):1330-1. doi: 10.1038/eye.2013.191.
Samarawickrama C, Ioannidis AS, Wechsler AW, Watson SL. Bilateral corneal infections associated with topical steroid therapy prophylaxis for cytarabine arabinoside-induced keratoconjunctivitis. Leukemia. 2014 Jan;28(1):220-2. doi: 10.1038/leu.2013.237.
Menghini M, Knecht PB, Kaufmann C, Kovacs R, Watson SL, Landau K, Bosch MM. Treatment of traumatic corneal abrasions: a three-arm, prospective, randomized study. Ophthalmic Res. 2013;50(1):13-8. doi: 10.1159/000347125.
Watson S1, Sarris M, Kuishek M, McKelvie P, Figueria E, McCluskey P, Coroneo M, Wakefield D. Limbal dermoid epithelium shares phenotypic characteristics common to both hair epidermal and limbal epithelial stem cells. Curr Eye Res. 2013 Aug;38(8):835-42. doi: 10.3109/02713683.2013.780625.
Ooi K, Watson SL. Improvements in Tear Film Stability. Sydnovate, The University of Sydney and NewSouth Innovations Pty Limited. Publication number WO2013113067, publication date 8th August 2013, Application number PCT/AU2013/000087
Watson S. Evidence For The Management Of Meibomian Gland Disease. Clinical and Experimental Ophthalmology. December 2012. 40:74-74.
Lee, Hugo & Barker, Neil & Watson, Stephanie. (2012). What Is The Best Treatment For Recurrent Corneal Erosions? A Cochrane Review Update. Clinical and Experimental Ophthalmology. December 2012. 40:33-34.
Brown T, Tan T, Cheng J, Taylor P, Watson S. The Diagnostic Value Of PCR In Acanthamoeba Keratitis. December 2012. Clinical and Experimental Ophthalmology. 40: 29-29.
Karsten E, Watson SL, Foster LJ. Diversity of microbial species implicated in keratitis: a review. Open Ophthalmol J. 2012;6:110-24. doi: 10.2174/1874364101206010110.
Watson SL, Lee MH, Barker NH. Interventions for recurrent corneal erosions. Cochrane Database Syst Rev. 2012 Sep 12;(9):CD001861. doi: 10.1002/14651858.CD001861.pub3.
Harkin DG, Apel AJ, Di Girolamo, Watson S, Brown K, Daniell M, McGhee JJ, McGhee CN. Current status and future prospects for cultured limbal tissue transplants in Australia and New Zealand. Clinical & experimental ophthalmology. September 2012. 41:10.1111/j.1442-9071.2012.02877.x.
Colman GWK, Wang M, Watson S. Direction of Arrival Estimation for MIMO Systems Employing Constellation-Based Precoding. Vehicular Technology Conference, 1988, September 2012 IEEE 38th. 1-5. 10.1109/VTCFall.2012.6399094.
Thomson K, Marcal H, Shabazi J, Watson, S, Wakefield D, Foster L. SurgiLux: A Novel Thin Film, Laser-Activated Bioadhesive for Corneal Repair. Advanced Materials Research. April 2012 506:7-10. 10.4028/www.scientific.net/AMR.506.7.
Menghini M1, Watson SL, Bosch MM. Corneal melting two weeks after pterygium excision with topical mitomycin C: successfully treated with lamellar keratoplasty and amnion membrane transplantation. Case Rep Ophthalmol. 2012 Jan;3(1):24-9. doi: 10.1159/000336452. Epub 2012 Jan 31.
Echevarria TJ, Chow S, Watson S, Wakefield D, Di Girolamo N. Vitronectin: a matrix support factor for human limbal epithelial progenitor cells. Invest Ophthalmol Vis Sci. 2011 Oct 17;52(11):8138-47. doi: 10.1167/iovs.11-8140.
Sanli E, Figueira EC, Bhardwaj G, Watson SL, Francis IC. Tunnel vision and night blindness in a 52-year-old man. Med J Aust. 2011 Sep 5;195(5):287-8.
Shahbazi J, Marçal H, Watson S, Wakefield D, Sarris M, Foster LJ. Sutureless sealing of penetrating corneal wounds using a laser-activated thin film adhesive. Lasers Surg Med. 2011 Aug;43(6):490-8. doi: 10.1002/lsm.21076.
Watson SL, Daniels JT, Geerling G, Dart JK. Clinical trials of therapeutic ocular surface medium for moderate to severe dry eye. Cornea. 2010 Nov;29(11):1241-6. doi: 10.1097/ICO.0b013e3181d82f5e.
Foster LJ, Thomson K, Marçal H, Butt J, Watson SL, Wakefield D. Chitosan-vancomysin composite biomaterial as a laser activated surgical adhesive with regional antimicrobial activity. Biomacromolecules. 2010 Dec 13;11(12):3563-70. doi: 10.1021/bm101028g.
Knecht PB, Kaufmann C, Menke MN, Watson SL, Bosch MM. Use of intraoperative fourier-domain anterior segment optical coherence tomography during descemet stripping endothelial keratoplasty. Am J Ophthalmol. 2010 Sep;150(3):360-365.e2. doi: 10.1016/j.ajo.2010.04.017.
Di Girolamo N, Watson S.Reply to Aniridia-To Be or Not To Be? Transplantation. Feb 2010. 89:483-4. 10.1097/TP.0b013e3181c832a8.
Di Girolamo N, Watson S. Reply to Contact Lens-Based Expansion and Transplantation of Autologous Epithelial Progenitors for Ocular Surface Reconstruction: Crossover Control. Transplantation. Feb 2010. 89:484. 10.1097/01.TP.0000368789.42492.f2.
Watson SL, Marcal H, Sarris M, Di Girolamo N, Coroneo MT, Wakefield D. The effect of mesenchymal stem cell conditioned media on corneal stromal fibroblast wound healing activities. Br J Ophthalmol. 2010 Aug;94(8):1067-73. doi: 10.1136/bjo.2009.165837.
Liu L, Tiffany J, Dang Z, Dart JK, Watson SL, Daniels JT, Geerling G. Nourish and nurture: development of a nutrient ocular lubricant. Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2932-9. doi: 10.1167/iovs.08-1991.
Di Girolamo N, Bosch M, Zamora K, Coroneo MT, Wakefield D, Watson SL. A contact lens-based technique for expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction.Transplantation. 2009 May 27;87(10):1571-8. doi: 10.1097/TP.0b013e3181a4bbf2.
Borovik AM, Bosch MM, Watson SL. Ocular pigmentation associated with clozapine. Med J Aust. 2009 Feb 16;190(4):210-1.
Watson SL, Secker GA, Daniels JT. The effect of therapeutic human serum drops on corneal stromal wound-healing activity. Curr Eye Res. 2008 Aug;33(8):641-52. doi: 10.1080/02713680802254790.
Watson SL. Suppurative keratitis. In: Wormald R, Smith L, Henshaw K, eds. Evidence-based Ophthalmology. London: BMJ books, Chapter 23
Watson SL, Coroneo M. Advances in the management of dry eye. Modern Medicine South Africa. 2009, July:28-35
Watson SL, Coroneo M. Advances in the management of dry eye. Med Today. 2008,
9:46-54
Watson SL, Barker NH. Interventions for Recurrent Corneal Erosion. Clin Experiment Ophthalmol. 2008, 36: A704
Watson SL, Coroneo MT. Ocular Rosacea: an approach to management. Med Today. 2007, 8:25-31
Watson S, Abiad G, Coroneo M. Spontaneous resolution of corneal oedema following Descemet's detachment. Clinical & experimental ophthalmology. December 2006. 34:797-9. 10.1111/j.1442-9071.2006.01319.x.
Hollick EJ1, Watson SL, Dart JK, Luthert PJ, Allan BD. Legeais BioKpro III keratoprosthesis implantation: long term results in seven patients. Br J Ophthalmol. 2006 Sep;90(9):1146-51.
Watson SL, Tuft SJ, Dart JK. Patterns of rejection after deep lamellar keratoplasty. Ophthalmology. 2006 Apr;113(4):556-60.
Kehdi EE, Watson SL, Francis IC, Chong R, Bank A, Coroneo MT, Dart JK. Spectrum of clear corneal incision cataract wound infection. J Cataract Refract Surg. 2005 Sep;31(9):1702-6.
Watson SL, Bunce C, Allan BD. Improved safety in contemporary LASIK. Ophthalmology. 2005 Aug;112(8):1375-80.
Watson S, Hollingsworth J, Coroneo M, Tullo AB. Correspondence. Confocal microscopy of Thygeson's superficial punctate keratopathy. Clinical and Experimental Ophthalmology. Feb 2005. 33: 111-111. 10.1111/j.1442-9071.2005.00964.x.
Watson SL, Daniels J, Geerling G, Dart J Pharmaceutical preparations for and treatment of ocular surface and other disorders. International Patent Application No PCT/GB2005/000806 published on 15 September 2005, publication number WO 2005/084635. US Patent Application No. 10/590,859.
Versace P, Watson SL. Cornea-sparing laser in situ keratomileusis: ablation on the flap. J Cataract Refract Surg. 2005 Jan;31(1):88-96.
Watson SL, Ramsay A, Dart JK, Bunce C, Craig E. Comparison of deep lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus. Ophthalmology. 2004 Sep;111(9):1676-82.
Akpek EK, Dart JK, Watson S, Christen W, Dursun D, Yoo S, O'Brien TP, Schein OD, Gottsch JD. A randomized trial of topical cyclosporin 0.05% in topical steroid-resistant atopic keratoconjunctivitis. Ophthalmology. 2004 Mar;111(3):476-82.
Watson SL, Coroneo MT. Corneal valance: a useful sign in epithelial basement membrane dystrophy. Eye (Lond). 2003 Jul;17(5):660-1.
Watson SL, Hollingsworth J, Tullo AB. Confocal microscopy of Thygeson's superficial punctate keratopathy. Cornea. 2003 May;22(4):294-9.
Verma S, Watson SL, Dart JK, Eykyn SJ. Bilateral Mycobacterium chelonae keratitis following LASIK. J Refract Surg. 2003 May-Jun;19(3):379-80.
Barker N, Watson S. Interventions for recurrent corneal erosions. The Cochrane Library. October 2002. 10:1002/14651858.CD001861.
Watson SL, Francis IC, Coroneo MT. Pituitary apoplexy presenting with an orbital bruit. Clin Exp Ophthalmol. 2002 Aug;30(4):305-7.
Watson S, Tullo AB, Carley F. Treatment of superior limbic keratoconjunctivitis with a unilateral bandage contact lens. Br J Ophthalmol. 2002 Apr;86(4):485-6.
McKelvie PA, Francis IC, Watson S, Nuovo G. Multifocal chorioretinal atrophy associated with herpes zoster ophthalmicus. Clin Exp Ophthalmol. 2001 Dec;29(6):429-32.
Watson SL, Coroneo MT. Steroids and the Eye. Med Today 2001;2:79-85
Watson SL, Coroneo MT. Steroids and the Eye. Modern Medicine Middle Eastern Edition. 2002;19:66-72
Watson SL, Westland K, Pollard JD. An electrophysiological and histological study of trypsin induced demyelination. J Neurol Sci. 1994 Nov;126(2):116-25.
Watson SL. Therapeutic Ocular Surface Medium: Clinical and in vitro studies. PhD Thesis. The University of New South Wales, 2006.